What are polynucleotides and why should I be offering them to my patients
Polynucleotides are long-chain molecules made up of nucleotide units, which are the basic building blocks of nucleic acids like DNA and RNA. Each nucleotide contains three components: a sugar (ribose in RNA, deoxyribose in DNA), a phosphate group, and a nitrogenous base.
In medicine and aesthetic treatments, polynucleotides are often used for their regenerative properties. They are typically derived from salmon DNA, as it's biocompatible and has minimal risk of immune rejection. Here’s why you might consider offering polynucleotide treatments to your patients:
1. Skin Regeneration and Anti-Ageing
- Wound healing: Polynucleotides stimulate tissue regeneration and wound healing by promoting the growth of fibroblasts, which produce collagen. This helps in restoring skin structure and function.
- Hydration and elasticity: They increase moisture retention and improve the skin’s elasticity, which can slow down or reverse the signs of ageing, such as wrinkles, fine lines, and sagging.
- Collagen production: By encouraging collagen synthesis, polynucleotides help to rebuild and repair damaged skin, leading to improved skin texture and a more youthful appearance.
2. Anti-inflammatory and Healing Properties
- Polynucleotides have anti-inflammatory effects that can help reduce redness, swelling, and irritation. This makes them useful for treating conditions like acne, rosacea, and other inflammatory skin issues.
- They can also be beneficial in post-procedural care to speed up recovery and reduce downtime after laser treatments, chemical peels, or microneedling.
3. Biostimulation
- Polynucleotides act as biostimulants, meaning they activate cellular repair processes and promote the regeneration of dermal tissues. This can result in an overall improvement in skin health and texture over time.
4. Minimal Side Effects
- Since polynucleotides are derived from DNA, their biocompatibility with human skin reduces the likelihood of allergic reactions or adverse side effects. They are generally well-tolerated by most patients.
5. Applications Beyond Aesthetics
- Polynucleotide treatments are also being explored for their benefits in ophthalmology (for dry eye treatment), orthopaedics (joint repair and cartilage regeneration), and other areas where tissue repair and anti-inflammatory action are needed.
By offering polynucleotide-based treatments, you can provide your patients with cutting-edge regenerative options that address skin health, ageing, and healing in a holistic and natural way.